Violin plot of NO of known AR target genes, which exhibit an AR-binding motif in their promoter based on MsigDB 75 , in Xq-Inv ( n = 18 cells) and WT cells ( n = 66 cells), all cell types (left), HSCs only ( n = 18 cells, upper-right) and MEPs ( n = 28 cells, lower-right). Boxplots were defined by minima, 25th percentile − 1.5× IQR; maxima, 75th percentile + 1.5× IQR; center, median; and bounds of box, 25th and 75th percentiles. P values are based on the two-sided likelihood ratio test followed by Benjamini–Hochberg multiple correction. The gray and yellow shading of violin plots show the genotype of cells (gray, WT; yellow, Xq-Inv).