Heatmap from Scientific Research

Construction of bone marrow and UCB-specific NO reference datasets to allow for cell-typing, based on subjecting HSPC cell types to index sorting, and scMNase-seq. Heatmap of single-cell NO of gene bodies of 305 single bone marrow HSPCs (UCB-based reference shown in Extended Data Fig. 2 ). The 819 signature genes depicted (rows) allow for discrimination between eight cell types (columns). Cells are grouped and color-coded by immunophenotype, determined by FACS. Example marker genes for each cell type are shown to the right of the heatmap, color-coded by the cell type. Differential NO of marker genes is represented by Z -scores.

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