ChrAcc (top) and cross-correlation between peaks (bottom) of CHRNA1 loci from pseudobulk single cells grouped as in f . The association of the CHRNA1 promoter ChrAcc across age is shown in the right panel. Correlation test: Pearson’s. For box plots, the upper and lower bounds of boxes show 25% and 75% percentiles of the data. The median of data is shown as the horizontal line in the box. The distribution minima and maxima, defined as farthest data point distanced ≤1.5 IQR from the box bounds, are shown by the whiskers. The violin plot shows the empirically estimated density distribution of data. Corr.coef., correlation coefficient.
