The total chromatin accessibility on ClockDML (ClockAcc), HMM-smoothened ClockAcc and initial and iterative EpiTrace ranking result (EpiTrace age) corresponding to the embryonic dataset. Sample numbers of biologically independent samples: n = 1 (Oocyte); 1 (Sperm); 2 (Zygote); 5 (two-cell); 1 (four-cell); 6 (eight-cell); 2 (Morula); 5 (ICM); 4 (Naive hESC); 7 (Primed hESC); 2 (TE); and 3 (Differentiated trophoblast). The upper and lower bounds of boxes show 25% and 75% percentiles of the data. The median of data is shown as the horizontal line in the box. The distribution minima and maxima, defined as farthest data point distanced ≤1.5 IQR from the box bounds, are shown by the whiskers. Correlation R and P value: Pearson’s. Tiny P values resulting in numerical underflow are shown as ‘<2.2 x 10 -16 ’. tropho., trophoblast.
