Richness (top) and clonality (bottom) of inferred tumor-reactive (+/−) clones using TRTpred in n = 5 cohorts: internal data (melanoma n = 14); ref. 14 (melanoma, n = 4); ref. 11 (GI, n = 5); ref. 8 (n = 1 melanoma, n = 2 breast and n = 12 GI); ref. 12 (lung, n = 4). Patients are color-coded according to the cancer type. Metrics are displayed in logarithmic scale and statistics were performed using a one-tailed t-test.
