Bar Plot from Scientific Research

The upper panels show microscopic pictures of human primary CD4 positive T cells activated by immobilized anti-CD3 and/or CD28 with or without panobinostat treatment ( n = 1). The lower panel shows a bar plot showing the average size of aggregates (shown in the upper panel) as a function of the applied HDAC inhibitor dose. Error bars indicate the standard deviation from n = 5 pictures. * P < 0.05, ** P < 0.01, *** P < 0.001 compared to DMSO treatment. Significance testing was done with one-way analysis of variance using F -statistics, followed by calculation of Tukey honest significant differences as post hoc test with confidence interval of 95% and correction for multiple comparisons. Scale bars, 400 m.

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