Bar plot (left) shows the number of pathogenic deletions in exons that contain an NGG (blue) or that contain an NGG and a templated insertion recovers the reference protein sequence and frame (green). Horizontal bar plots (right) show the predicted scission profile of gRNAs targeting pathogenic deletions with LZ3 or SpCas9. Blunt indicates gRNAs with blunt rate > 0, staggered < 0 and highly staggered -2.
