UMAP from Scientific Research

Single-cell maps of CRE activity for four CREs (separate panels). Each point represents a single cell. Gray indicates cells with no reporter detected (ND: no detection) for the specified CRE. The color marks reporter expression (average normalized mBC UMI per cell) from none (black) to high (red) for cells with detected reporters (oBC UMI >10). The color axis is truncated to 4 UMIs. Elements chr3_2007 and chr3_2009 have significant expression specific to pluripotent cells (carets) (Fig. 4a, marginal activity from chr3_2005 significant in only one of three biological replicates), mirroring Sox2 expression in that cell type (c.f. d). The number of cells with detected reporter integrations is indicated on each panel.

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