CellSpace applied to human cortex chromatin accessibility data by joint embedding of two datasets: the scATAC-seq readout of the multiome dataset with 8,981 cells (Fig. 3a ) and a (single-modal) scATAC-seq with 12,675 cells, processed with respect to their own peak atlases. The Venn diagram shows the top 50,000 most variable peaks from each assay, with 31,800 peaks in each atlas having nonzero overlap with the other atlas. The UMAP of the joint CellSpace embedding shows cells from each dataset, overlaid with cell type annotations from the original study. MG, microglia.
