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Identification of the interface of A1E1 (E1 domain of APLP1) binding to L3D2 (D2 domain of LAG3). Overlay of the 2D 1 H- 15 N HSQC spectra of A1E1 alone (gray) and in the presence of 2 molar folds of L3D2 (blue). Four residues with significant calculated chemical shift deviations (CSDs) (> 0.03 ppm) are highlighted and enlarged in the black boxes.
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