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Quantification of co-localization of α-syn-biotin PFF and Rab7 in WT neurons transiently expressing full-length Aplp1 (FL: 25 cells) and deletion mutants: ΔE1(10 cells), ΔAcD + E2 (12 cells), ΔICD (15 cells), App (5 cells) and Aplp2 (5 cells), and control (16 cells) from 3 independent experiments. (p-values: FL vs. Control <0.0001, FL vs. ΔE1 < 0.0001, FL vs. ΔAcD + E2 0.0178, FL vs. ΔICD 0.0831, FL vs. App < 0.0001, FL vs. Aplp2 < 0.0001).
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