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Closed state dwell time CDFs of pores formed under indicated experimental conditions. n = 7 (for Munc18-1), n = 3 (for no SNARE chaperones and Munc18-1(D326K) independent BLMs; at least three sets of NDs were used for each experimental condition. Data are presented as mean ± SEM; Students t -test (two-tailed) was performed to compare the two means; ** p <0.01, *** p < 0.001. Relevant source data are provided as a Source Data file.
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