Forest Plot from Scientific Research

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Forest plot of the most significant SNPs in the GWAS for expanded clonal size demonstrating their coefficients and -log(p-value) in the GWAS of passenger-approximated clonal expansion rate. The effect estimates were derived from a linear mixed model with kinship adjustment regressing inverse normally transformed total passenger mutations, with age, sex, clonal fraction, study, and the first 10 ancestral principal components included in the model as covariates. Genes annotated based on OpenTargets variant annotations. SNPs with beta <0.025 not shown. Data are presented as mean values±1.96*SE.
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