Reciprocal dilutions of serum required to inhibit 50% virus infection are shown in panels. Data in A-D were analyzed by mixed-model ANOVA with Greenhouse-Geisser correction and Sidak’s multiple comparisons test to compare differences with luciferase (control) mRNA immunization. Day 28 * P < 0.0001, day 56 * P = 0.0005; Source data are provided as a Source Data file.
