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Antibody prediction quality increases with the number of model seeds. The quality of top-ranked, low-homology antibodyantigen interface predictions as a function of the number of seeds. Each datapoint shows the mean over 1,000 random samples (with replacement) of seeds to rank over, out of 1,200 seeds. Confidence intervals are 95% bootstraps over 10,000 resamples of cluster scores at each datapoint. Samples per interface are ranked by proteinprotein ipTM. Significance tests were performed using by twosided Wilcoxon signed-rank tests. n = 65 clusters. Exact P values were as follows: 2.0 x 10 -5 (percentage correct) and P = 0.009 (percentage very high accuracy).
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