Left, representative example of CeA µOR-expressing neurons co-localizing with cFOS (white arrows) after precipitated withdrawal. Right, fraction of cFOS-expressing neurons among CeA µOR or SST-expressing neurons (n = 8 mice for SST and n = 8 mice for µOR; two-sided unpaired t -test, *** P < 0.0001). Scale bar, 20 µm.