Left, box plot of precipitated jump ( h ) and immobility ( i ) withdrawal symptoms after µOR deletion in indicated brain areas (CTL, n = 12; VTA, n = 13; NAc, n = 13; BLA, n = 12; CeA, n = 14; PVT, n = 13). Right, proportion of mice showing the presence of at least one precipitated jump ( h ) and at least 5 min of immobility ( i ) withdrawal symptoms. Kruskal–Wallis test: jumps, H (6) = 15.39, P < 0.01; immobility, H (6) = 8.774, P = 0.12; Dunn’s multiple comparisons test, * P = 0.0218. In box plots, the centre line is the median, box edges delineate first and third quartiles, and whiskers extend to maximum and minimum values.
