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Proportions of genes in clusters 4-6 in UKB compared with simulations. The proportion of genes where pLoFs in the UK Biobank are clustered into clusters 4-6 against the number of pLoFs in that gene is shown in blue. The proportion of simulated genes where pLoFs clustered into clusters 4-6 against the number of variants in the gene is shown in red. The green line shows the number of genes with each number of pLoFs in UK Biobank. The X -axis is log10-transformed
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