The top panel shows the frequency of non-synonymous mutations in each sample. The main panel shows the occurrence of major somatic mutations across different samples, with different colors correspond to different mutation categories. Genes involved in these mutations are grouped based on their biological functions indicated on the left. The overall frequency of these somatic mutations across all examined samples are shown on the right. The lower panel indicates the sampling status (primary vs. relapsed/refractory), sequencing methods (WGS vs. WES), and Ann Arbor stage (I/II vs. III/IV) of each sample.
