The multi-scale cell-type spatial relationship trend plot for Intermediate mesoderm cells as the reference cell type for CRAWDAD, with neighboring cell-types Lateral plate mesoderm and Cardiomyocytes highlighted in red and blue, respectively. All other neighboring cell types in gray. The horizontal black dotted lines in ( h ) represent the Z -score significance threshold corrected for multiple testing (Z-score = 3.88). The vertical red bars ( h ) represent the error bars of one standard deviation from the mean Z -score estimated using permutations.