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Quantification of fraction of OSBP-positive insulin granules in MIN6 cells and mouse islet β cells treated with OSW-1 (20 nM for 20 min) or DMSO (basal). Each dot represents the mean of one experiment and line shows mean for all experiments (∗∗p < 0.01,∗∗∗∗p < 0.0001; n = 6 and 3 experiments with >50 cells or >10 islets per experiment, two-tailed, unpaired Student’s t test).
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