Number of MDMs returning to the scratch from young human MDMs with loss of MYC or USF1 over 14 h. Data are presented as mean ± SEM with each data point representing the mean of six donors, each done in triplicate. N= 6, two-way ANOVA with Tukey’s multiple comparison,*p< 0.05,**p< 0.01. Control, non-targeting siRNA control; siMYC, MYC-targeting siRNA; siUSF1, USF1-targeting siRNA; M0, cells left unstimulated; MLPS+IFNγ. cells stimulated with LPS and IFN-γ stimulated for 24 h. ns, not significant.
