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Open access visualization of Pie Chart, TF Target Genes, Macrophages, Dysregulation, Age
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Percentage of TF target genes expressed in macrophages that are dysregulated with age. Foxm1, 45 differentially expressed/of 83 targets; Nfic, 73/202; Srf, 82/263; Myc, 412/1,336; Nfyb, 886/3,004; Usf1, 352/1,200. Differentially expressed genes with age (logFC > 1.5) were identified in GEO:GSE84901 microarray dataset comparing alveolar macrophages from young (2–4 months, N= 6) and aged (22–24 months, N= 6) C57BL/6J mice.

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