Microscopy from Scientific Research

H&E staining and NQO1 immunostaining of esophagus and forestomach of wild-type,Nrf2L30F/L30F::K5Cre, andKeap1flox/flox::K5Cre mice. Double-headed arrows and arrowheads indicate hyperkeratosis and dysplastic squamous cells, respectively. Yellow lines indicate hyperplasia of squamous cell basal layer in forestomach. Scale bars, 100 μm. Data are expressed as mean ± standard deviation (SD). Statistical significance in (F) was determined by Tukey’s multiple comparison test (*p< 0.05,***p< 0.001).

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