Sequence logos of S7b positions (gray box) from alignments of insect GRs, ORCOs, and insect ORs (green, polar amino acids [G, S, T, Y, C, Q, N]; blue, basic [K, R, H]; red, acidic [D, E]; and black, hydrophobic [A, V, L, I, P, W, F, M]). Residues interacting with the pore-penetrating lipids are marked with stars (polar) or arrowheads (aliphatic) colored according to (D) and (E). Black arrowheads mark pore-gating residues. See also Figures S8 and S9.