Scatter Plot from Scientific Research

mRNA levels of essential hepatocyte marker genes. Representative mRNA samples from different individuals, differentiation batches, stages (day 0, 2.5, 7, 13, and 18), and with different genotypes (control = HEL24.3, edited, and not edited) were analyzed by qPCR. The mRNA levels are expressed in fold change and normalized to the HepG2 commercial hepatocarcinoma cell line (illustrated with a yellow line at the fold change 1 on the y axis when the scale allows it). Each point represents an independent hiPSC line, which we consider a biological replicate. Data are represented as the mean ± SEM. Statistical significance based on Tukey test; p > 0.05 (ns, not significant), p < 0.05 (*), p < 0.01 (**), p < 0.001 (***), p < 0.0001 (****).

DOI