Quantification of explained variance for opto-fMRI activations from direct projections and low-dimensional structural networks (as in C), respectively. Statistical significance was calculated by two-tailed paired t test. Notably, the null control was constructed by spatially shuffling the BOLD activation maps. Each dot represents an individual EPI run. Box, 25%–75% range and median line; whisker, minimum to maximum range; plus mark, the mean value.
