Bar Plot from Scientific Research

Open access visualization of Bar Plot, Clustered, Proteomic Screen, Viral Mutants, DMXL1
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A proteomic screen of viral block deletion mutants determined that the US29-34A gene block is required to downregulate DMXL1. Bars of same color represent biological replicates, and all viruses were examined in duplicate or triplicate across three independent experiments (data from Nightingale et al.). Fold change was calculated in comparison with strain Merlin wild-type 1 (WT1) control. A second control was included, comprising WT1 that lacked UL16 and UL18 genes. Strain AD169 HCMV was used as the UL/b strain in this study, and we confirmed that AD169 as well as Merlin-strain HCMV downregulates DMXL1 (Figure S2B).

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