Protein Structure from Scientific Research

Space-filling diagrams comparing the priming and chain extension intermolecular interfaces between UBE2R2 (light blue) and FEM1C (purple). Whereas approximately 400 A2of surface area is buried between UBE2R2 and FEM1C in the priming structure, conformational changes have shifted the poly-ubiquitylation interface such that only ~200 A2of surface area is buried.

DOI