The enrichment of pluripotency exit and naive-associated genes in 24 h multiway hubs (very similar results were obtained when analyzing the separate Rex1-high and Rex1-low [formative state] cells [data not shown]). The colors shown in the heatmaps in (C) and (D) indicate the log fold change in gene abundancewe compared the top 30% most intermingled A compartment regions with the bottom 30% and contacts observed within 24 h state multiway hubs to the genome-wide distribution (seeSTAR Methods). FDR-adjusted empirical p values:*p < 0.05;**p < 0.01;***p < 0.001.
