Slices through 3D genome structures of representative single G1 phase nuclei, where the individual chromosomes are colored differently (top), colored blue or red depending on whether a particular region of a chromosome is in the A or B compartment, respectively (middle), or colored yellow or blue depending on whether that particular region of the chromosome is either intermingled with another chromosome or buried (bottom). Regions transitioning between the two are colored gray. Five independently calculated 25 kb structures are superimposed to show that the structures are well determined by the Hi-C data.