(Left) An intermingling score was defined as the fraction of beads (in the polymer model of the 3D genome structure) that are located on different chromosomes and in close spatial proximity. (Right) Violin plots of the inter-chromosome intermingling scores of genomic loci determined from the 3D structures show a significant increase in intermingling of A (and to a lesser extent B) compartment regions in 24 h state cells. Related to Figure S2.