Illustration from Scientific Research

Schematic of types of interfaces between different genomic regions on the same chromosome. A smooth interface (top) will result in a C-walk (black dashed arrow) with most steps within each region, and fewer steps between the two regions (indicated by small black solid arrow). An entangled/intermingled interface (bottom) will result in a C-walk (black dashed arrow) with more steps between the two regions (indicated by small black solid arrows).

DOI