Microscopy from Scientific Research

Lysosomes of cells expressing SPG20 WT or the 8xV mutant along with mCherry-Gal3 were loaded with the photosensitizer AlPcS2a. Indicated areas were laser-irradiated to induce lipid peroxidation. Translocation of Gal3 and SPG20 was followed over 15 min in live cells. Scale bars: 5.

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