Microscopy from Scientific Research

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Direct binding of SPG20 to lipid-packing defects. Giant unilamellar vesicles (GUVs) were generated without or with conical lipid DOG that induces lipid-packing defects. GUVs were incubated with purified Alexa488-labeled SPG20 wild type or 8xV mutant. Scale bars: 10 m.
#Microscopy#Binding#SPG20#Lipid-Packing Defects#GUVs#Conical Lipid DOG#Alexa488-labeled SPG20 Wild Type#8xV Mutant
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