Scatter Plot from Scientific Research

Antibody binding titers (expressed as half-maximal effective dilution [ED50]) against XBB.1.5 S in XBB.1.5 S booster-elicited vaccinee plasma that were either mock-depleted (left) or depleted (right) of antibodies recognizing Wuhan-Hu-1 S as determined by ELISA. Samples were collected 7–13 days (mean: 10 days) after receiving the XBB.1.5 S mRNA booster. The dotted lines indicate the limit of detection of 1/50 for the ELISA. Each data point represents the half-maximal effective dilution (ED50) for an individual obtained from averaging technical duplicates from one representative out of 2 biological replicates. Geometric mean titers (GMTs) for each cohort against each pseudovirus are shown as bar graphs. See also Figures S3 and S4.

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