Illustration from Scientific Research

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Targeted alleles without (KPCBhet) and with (KPCBnull) tissue-restricted CRE-mediated deletion of Brca2 exon 11 in the pancreas. The Brca2Tr1492 allele emulates germline Brca2 heterozygosity in all somatic tissues.
#Illustration#Workflow#Targeted Alleles#CRE-mediated Deletion#Brca2 Exon 11#Pancreas#Brca2 Heterozygosity#Somatic Tissues
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