Previous non-CRC cancer, high blood pressure and diabetes treatment are associated with the distribution of diagnosis groups. The patients with CRC have a higher proportion of previous cancer (47.5% versus 15.0 % and 12.1%, two-sided CS test, CV effect size of 0.24, χ 2 = 31.65, d.f. of 2, adjusted P = 1.98 × 10 −2 ) and high blood pressure (60.0% versus 44.3% and 30.5%, CV of 0.17, two-sided CS test, χ 2 = 16.55, d.f. of 2, adjusted P = 1.98 × 10 −2 ) while the CTL group has the lowest proportion of patients with diabetes treatment (2.4% versus 10.3 and 10.6, two-sided CV effect size of 0.15, CS test, χ 2 = 13.79, d.f. of 2, adjusted P = 1.98 × 10 −2 ).
