The shared introgressed genomic region on subCC chromosome 4 contains a cluster of R genes ( RPP8 ), a cluster of homologs of a negative regulator of R genes ( CPR1 ) and a cluster of homologs of Leaf rust resistance 10 kinases ( LRK10L ) (bottom). The heatmap shows, from the bottom up, (1) log fold change of gene expression after H. vastatrix inoculation, when comparing resistant Timor hybrid lineage against a susceptible cultivar; red color means elevated expression in the hybrid, and blue decreased expression. (2) Fixation index ( F ST ) values for the introgressed lines versus cultivars and between cultivars and wild accessions. (3) Nucleotide diversity for the wild and cultivated accessions for each gene coding region, plus the flanking 2 kb upstream and downstream of the region. FC, fold change.