Shown are the association between rs738409 carrier status and risk of five liver outcomes according to BMI categories (<30 versus >=30 kg m - 2 ), weekly alcohol intake (<=14 versus >14 weekly drinks) and T2D (no versus yes). Points refer to OR (measure of center), error bars represent 95% CIs and P represents P value for interaction. We used logistic regression models, adjusted for age, sex and ten principal components (PCs). Interactions between the variant and environmental factors were evaluated using likelihood ratio tests, comparing a main-effect model (variant + environmental factor) with a model including an interaction term (variant x environmental factor). The number of exposed individuals and the number of outcomes within each subcategory are listed in Supplementary Table 15.
