Receiver operating characteristic curve and precision–recall curve of binding potential for ETS1 in naive CD4 T cells. The ground truth for a and e is the ChIP-seq data of ETS1 in naive CD4 + T cells. The color in a – e represents the different methods used to predict TF–RE regulation. Orange, LINGER; green, PCC between the expression of TF and the chromatin accessibility of RE; blue, motif binding affinity of TF to RE.