The interactions are also shown on the structure of IgG3-M1 with black lines for both Hbonds and Salt-bridges. The residues involved in the interactions are shown as spheres. The two chains of protein M1 are colored in light and dark purple, and the VH (variable heavy), CH1 (constant heavy domain 1), VL (variable light), and CL (constant domain light chain) domains are shown in light green, dark green, pink, and red, respectively. The IgG-M1 models in the figure are the starting models for the MD simulations.
