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The human VICs were cultured in an osteogenic medium for 3 weeks in the presence or absence of BBT-877 (1 M), and the indicated cytokines were measured by ELISA. E Cytokines related to osteogenesis. Data are presented as the mean SD of triplicate ELISA tests. A representative set of results from more than three independent experiments is presented. * P < 0.05, ** P < 0.01, *** P < 0.001 versus vehicle control. P values were obtained using a two-tailed t -test

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