Functional motifs for which gains or losses of the motif instances are associated with significant changes in chromatin accessibility. The motifs associated with increased chromatin accessibility (opening) are shown in red and those associated with decreased chromatin accessibility (closing) are colored in green. The y-axis represents the Student’s t -test statistic value. Two motif families (one for transcriptional activators and one for transcriptional repressors) are highlighted on the x-axis.
