The horizontal bar plots of evolution path analysis (A) and clonal selection analysis (B) with mutated gene expression. metastasis versus primary (LC: Metastasis panel) and progression disease (PD), partial response (PR), and stable disease (SD) in lung cancer (LC: drug-response panel). good response and poor response in CML sampled at diagnosis (CML: drug-response panel). Only the top 5 cancer signatures and top 5 metabolisms for metastasis, PD, and poor response with q value <= 0.1 were shown. The bar indicates the mean Spearman correlation coefficient for each group. The standard error is shown as an error bar. Terms in red are cancer related and black metabolism related.