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The foci in the nucleus with a diameter over 200 nm were included. ROS assay ( c ) in mMettl14f/f or mMettl14 -/- macrophages transfected with vector (-) or plasmids encoding FLAG-tagged WT or T72A mutants of Mettl14, and WT or Mettl14 T72A macrophages infected with H37Rv or H37Rv(ΔEsxB) (MOI = 5) for 4 h in ( c ). Results in c reflect the mean ± SEM from at least three independent biological experiments. Two-tailed unpaired Student’s t -test were used.

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