HAQ-Disability Index (A), HAQ pain scale (B), EQ-5D (C), and EQ-5D VAS (D), over 24 months. The end of study and end of treatment are indicated. SD at baseline for these measures are 0.7 for HAQ-Disability Index, 26.7 for HAQ pain scale, 0.10 for EQ-5D, and 22.3 for EQ-5D VAS. HAQ=Health Assessment Questionnaire. VAS=Visual Analogue Scale.