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Schematic diagram of adoptive transfer experiment. On day -1 (1 day before infection), equal numbers of Ly49H+NK cells from WT mice and CD48 KO mice were mixed and injected intravenously into Ly49H KO recipients versus recipients lacking specific types of immune cells, including RAG-2-IL-2Rgamma DKO mice, RAG-1-Ly49H DKO mice, or Ly49H KO mice treated with alpha-CSF-1R or clodronate-containing liposomes. On day 0, 7.5 x 10^2 pfu of MCMV was injected intraperitoneally into recipients. The proportions and numbers of WT and CD48 KO NK cells in the Ly49H+NK cell population were analyzed in the blood or spleen at day 7.

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