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As in Figure 1H, shows strength of functional connectivity as a function of distance, but calculated on the time course of cortex-wide neural activity reconstructed from motifs. As in original data, long-range functional connectivity differed between groups: for 3–4.5 mm saline = 1.24 CI: 1.19–1.26; VPA = 1.16 CI: 1.11–1.23 p = 0.042; for 4.5–6 mm saline = 1.11 CI: 1.07–1.15; VPA = 1.00 CI: 0.94–1.08 p = 0.008. Data points reflect individual mice, except for (C), where they reflect motifs. Error bars in (D) show mean ± SEM. Solid and dotted lines in (A)–(C) show least-squares fit and 95% confidence bounds, respectively. All p values estimated with permutation tests. See also Figures S2 and S3 and Table S1.
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