Protein Structure from Scientific Research

Model of the CENP-E2055-2608generated by combining Alphafold2 models of its monomeric kinetochore-targeting domain and dimeric outer corona-targeting domain. The conserved residues 2527-2538 essential for corona targeting are in stick and ball mode and painted orange. The domain crystallized (F) is painted yellow. The residues essential for interaction with BubR1 are in red, and the conserved DFSE motif is painted magenta. SeeFigures S2F andS3.

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